PRIME IV HYDRATION & WELLNESS Franchise
Prime I.V. is the #1 I.V. hydration brand in the U.S.—a turnkey wellness empire-in-a-box with high margins, national momentum, and the power to turn your passion for health into a purpose-driven, profitable business.
$150,000
$49,000
154
2019
Colorado Springs,CO
Amy Neary
About PRIME IV HYDRATION & WELLNESS
Prime I.V. Hydration and Wellness is the nation’s fastest-growing I.V. hydration franchise, offering a premium “1 Hour Vacation” experience focused on preventive health and personalized wellness. Named the #1 I.V. brand by Entrepreneur Magazine in their Annual Franchise 500 Awards, Prime has over 300 locations open or in development nationwide. With proprietary I.V. formulas, advanced peptide therapies, and bioidentical hormone replacement therapy (BHRT) for both men and women, Prime delivers real, measurable results—boosting energy, immunity, and vitality in a luxurious spa-like environment.
What sets Prime apart is its commitment to empowering franchisees with a turnkey business model, comprehensive Prime Academy training, strong brand recognition, and multiple revenue streams including memberships and premium services. Whether hands-on or semi-absentee, owners can build a scalable, profitable business with strong ROI while making a meaningful impact in their communities. Prime I.V. is more than a franchise—it’s a movement toward accessible, science-backed, personalized healthcare.
Franchise Unit Trends & Revenue
154
59
$567,075
* in 2024
Franchise Fees
$49,000
7.0%
Gross Revenues
1.0%
Gross Revenues
Why Choose PRIME IV HYDRATION & WELLNESS?
- Award-Winning Brand: Named the #1 I.V. brand in Entrepreneur Magazine’s Franchise 500 Awards, Prime I.V. is a recognized industry leader with 300+ spas open or in development nationwide.
- Booming Industry: The wellness and preventive health market is exploding, and Prime sits at the intersection of luxury and science-backed care—making it a standout in a fast-growing field.
- Turnkey Business Model: From day one, franchisees receive comprehensive support through Prime Academy, covering operations, clinical training, marketing, and ongoing business development.
- Multiple Revenue Streams: Prime offers customized I.V. formulas, peptide therapies, and BHRT for men and women, alongside recurring revenue through memberships and package plans.
- Strong ROI Potential: High-margin services and a streamlined model allow for quick ramp-up and healthy returns—many franchisees reach profitability within months.
- Flexible Ownership: Suitable for hands-on operators or semi-absentee owners with a manager in place.
- Proven Leadership: Backed by founders with decades of experience in healthcare and franchising, Prime delivers vision, innovation, and support to help franchisees succeed.
Starting Costs & Investment Requirements
$300,000 - $600,000
$300,000
$150,000
Training & Support
Prime I.V. Hydration and Wellness provides an unmatched level of training and support to ensure every franchisee feels confident from day one—and supported every step of the way.
Our comprehensive Prime Academy includes:
- A multi-day, in-person onboarding program covering operations, clinical protocols, compliance, customer experience, and marketing
- Hands-on training for both owners and staff at a live, operating Prime spa
- Guidance on hiring, staffing models, and managing clinical personnel
- Real estate, construction, and spa setup assistance
- Launch support with pre-opening marketing and business development strategies
Once open, franchisees benefit from ongoing support, including:
- Regular coaching calls and performance reviews
- Access to proprietary systems, SOPs, and operational playbooks
- National and local marketing support
- Continuous education on emerging therapies and best practices
- A collaborative network of franchisees and an experienced corporate team committed to your success
- You’re in business for yourself, but never by yourself at Prime I.V.
History
Prime I.V. Hydration and Wellness was founded in 2018 by Amy Neary, a passionate healthcare entrepreneur who had already been serving the Colorado Springs community since 2008 through her affordable lab testing company. She saw a growing need for accessible, preventive wellness solutions—especially for individuals struggling with high-deductible insurance plans or limited healthcare access. Prime I.V. was created to fill that gap, offering customized I.V. hydration, vitamin therapy, peptides, and BHRT (bioidentical hormone replacement therapy) in a calming, spa-like environment.
Despite launching its franchise program in early 2020—just as the world shut down—Prime not only endured but thrived. Through a unique client experience known as the “1 Hour Vacation,” Prime quickly attracted a loyal customer base and visionary franchisees. Today, Prime has grown to 300+ open and in-development spas nationwide and is consistently ranked the #1 I.V. brand by Entrepreneur Magazine. With a clear mission and proven model, Prime is poised for long-term, purpose-driven success.
Ideal Candidate
Successful Prime I.V. franchisees come from a variety of backgrounds—what unites them is a passion for wellness, a drive to make a difference, and a commitment to operational excellence. You do not need a medical background to own a Prime franchise; however, a willingness to hire and lead a qualified clinical team is essential.
We’re looking for candidates who have:
- Strong business acumen and leadership skills
- Experience managing teams or customer-facing businesses
- A desire to positively impact their community through health and wellness
- The ability to follow a proven, turnkey system
- Interest in scaling with multiple locations over time
- Capital to support startup and ramp-up phases
- Whether you're a seasoned entrepreneur, investor, medical professional, or corporate escapee, Prime offers the tools, support, and structure to help you thrive. Semi-absentee ownership is possible with the right management team in place.