Missouri

Medical Practices For Sale in Missouri

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Market Info
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User-Ready Medical Office + Highway Frontage

Auction by Ten-X™

Washington, MO

Online auction: September 28-30, 2026

7,000 SF Medical For Sale...

Not Disclosed

31
Starting bid:

Not Disclosed

REAL ESTATE INCLUDED

listing-image
Medical Spa - well established, profitable turnkey

Jackson County, MO

Turnkey, modern, profitable medical spa offering prime aesthetic/cosmetic treatments with a focus on painless technique and best-friend experience that no competitor can duplicate. Extensive client...

Not Disclosed

Not Disclosed

EBITDA: $250,000

listing-image
Medical Practice

St. Louis County, MO

Highly profitable medical practice with 2000+ patient list from two locations. Very positive reputation for past 20+ years. For additional information please contact listing agent Greg Dyer at (636)...

$980,000

$980,000

Cash Flow: $387,405

Established Midwest Mobile Insurance Examination Provider

St. Louis County, MO

A rare opportunity to acquire a long-established mobile paramedical services provider with broad regional coverage, an experienced field network, and a growing clinical blood draw segment. More than...

$500,000

$500,000

Cash Flow: $166,685

Outpatient behavioral health practice in-network with insurance payors

St. Louis City County, MO

Fast growing outpatient mental health therapy clinic in St. Louis with brick and mortar location offering in-person and telehealth that is in-network with all major commercial and government payors....

$1,300,000

$1,300,000

Cash Flow: $215,000

$832K EBITDA Non-Surgical Medical Practice | No Medical License Needed

Kansas City, MO

Average SDE: $832,294/year (3-Year Average) Established, multi-unit non-surgical medical practice generating an average of $3.5M+ in annual revenue and $832K+ in EBITDA over the last three years....

$2,700,000

$2,700,000

EBITDA: $832,294

Greater St. Louis, MO Plastic Surgery Clinic for Sale

St. Louis, MO

Established plastic surgery and medical spa practice serving the Greater St. Louis metropolitan area for over a decade. This premier facial plastic surgery clinic has built a stellar reputation...

Not Disclosed

Not Disclosed

EBITDA: $708,000

Turnkey Schlerotherapy Practice - SBA Prequalified

St. Louis County, MO

SBA PRE-QUALIFIED - Are you a general or plastic surgeon, dermatologist or other physician seeking patient care, freedom and independence from the restrictive hospital and health insurance system?...

$950,000

$950,000

Cash Flow: $343,489

High-Volume Urgent Care Practice with Expansion Potential

St. Louis County, MO

Founded more than a decade ago, this well-established medical practice offers both urgent care and primary care services through a high-volume, walk-in model that has built a strong presence within...

$1,750,000

$1,750,000

Cash Flow: $300,000

Mental Health Company (MO)

Saint Louis, MO

The company has operated continuously since 2013, establishing itself as a recognized and trusted outpatient mental health practice in the St. Louis market. The practice operates under a boutique...

$1,200,000

$1,200,000

Cash Flow: $434,000

WCH Service Bureau
Franchise

Available Nationwide

WCH Medical Billing Franchise: proven model, software, training, and step-by-step support to operate and scale.

$45,000

$45,000

$567K SDE Non-Surgical Medical Practice | No Medical License Needed

Kansas City, MO

Average SDE: $567,000/year (3-Year Average) Established non-surgical medical practice generating an average of $2.3M+ in annual revenue and $567K+ in SDE over the last three years. Unlike many...

$1,800,000

$1,800,000

Cash Flow: $567,415

Turnkey Mental Health Practice

Wentzville, MO

Exceptional opportunity in the St. Louis, MO region! This established psychiatric practice is fully staffed with experienced therapist, nurse practitioners, and dedicated office personnel, ensuring...

$2,900,000

$2,900,000

Cash Flow: $738,978

Profitable Chiropractic Practice for sale in St Charles County Mo

St. Charles County, MO

Established 47-year-old chiropractic office with a strong history of profitability. Consistent gross annual revenue, a loyal patient base, excellent online reviews, and a prime location in St Charles...

$600,000

$600,000

Cash Flow: $17,289

Buy or Sell a Medical Practice in Missouri
Medical practices listed on BizBuySell include solo practitioner offices, multi-provider clinics, and specialty healthcare businesses across primary care and fields such as dermatology, pediatrics, optometry, chiropractic care, physical therapy, pain management, oncology, endocrinology, and surgery. Business models range from insurance-based practices to cash-pay clinics and hybrid models. Many listings feature established patient panels, credentialed staff, EMR systems, insurance billing infrastructure, and long-standing referral networks. Revenue is typically generated through patient visits, diagnostic services, procedures, and ancillary offerings. Some practices also include real estate, medical equipment, or turnkey operations—providing licensed professionals and healthcare investors with opportunities for growth, stability, and long-term value in the healthcare services market.
Market Overview Listings for Sale (Median) Total Missouri Market (Average)
Number of Businesses Analyzed10 1,901
Asking Price$1,250,000-
Reported Revenue$1,210,475 $1,128,976
Reported Seller's Discretionary Earnings$343,489 $170,331
Financials based on businesses that listed an asking price, annual revenue, and seller's discretionary earnings.
For more in-depth sales and profitability data see:

Asking Price

Lower QuartileMedianUpper Quartile
$957,500$1,250,000$1,787,500

Market Financial Highlights

The financial data presented here is an aggregation of reported revenue and earnings of Medical Practices for sale in Missouri.

BoundRevenueSeller’s Discretionary Earnings
Lower Quartile$812,926$215,000
Median$1,210,475$343,489
Upper Quartile$1,762,046$434,000

Valuation Multiples

The valuation multiples listed below are derived from asking price, revenue, and seller's discretionary earnings of Medical Practices listed for sale in Missouri.

BoundRevenue MultipleEarnings Multiple
Lower Quartile0.762.77
Median0.863.17
Upper Quartile2.065.83

FAQ's

How much does it cost to buy a Medical Practice in Missouri?

The median asking price for an established Medical Practice in Missouri is $1,250,000, though prices range from under $957,500 to well over $1,787,500.

How much do Medical Practices owners in Missouri earn?

The median reported revenue of Medical Practices in Missouri is $1,210,475 and owners earn a median of $343,489, which includes the owners salary and any other financial benefits they receive.

How do I value a Medical Practice?

Valuing a business is a complex process, but buyers and sellers often turn to the local market to understand how businesses are priced. Based on our most recent analysis of Medical Practices in Missouri, revenue multiples range from 0.76 to 2.06, with a median of 0.86. Earning multiples range from 2.77 to 5.83, with the median at 3.17. This means the typical Medical Practice in Missouri may ask for around 0.86 times its annual revenue, and 3.17 times its annual owner earnings.

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