Businesses For Sale in Greenville County, SC

Simpsonville, SC

Established and growing, one-on-one assisted stretching facility located in a high- growth, high earning demographic region within the Greenville, SC metro area. Greenville, SC is consistently...

Greenville, SC

Multiple concepts in a unique development with outdoor seating, stage, outdoor TV and green area. Liquor exclusivity for the entire project. Great downtown location....

Greenville County, SC

Are you looking to invest in a thriving health and wellness business? Look no further than this established Fitness Yoga Studio in South Carolina, United States. With a successful track record and a...

Greenville, SC

This is a rare opportunity to acquire a fully built-out, turnkey barbershop in a high-traffic retail center on Pelham Road in Greenville, SC. The shop is already established and generating...

Simpsonville, SC

Axe Throwing & Social Games Pub - Downtown Simpsonville Entertainment Venue This established entertainment business combines axe throwing with a social bar concept in downtown Simpsonville's vibrant...

Available in South Carolina

With over 26 years of experience and 100+ locations across the United States, DoodyCalls offers the perfect opportunity for entrepreneurs looking to start a rewarding business in the pet industry!

Greenville, SC

This outdoor home care business provides specialized treatments and exterior services designed to make residential yards more comfortable, attractive, and usable. Built on years of operational...

Greenville, SC

Established and fully operational laundromat located in Greenville, South Carolina. This approximately 2,000 sq. ft. facility is equipped with 17 washers and 17 dryers in multiple sizes and offers...

Greenville, SC

Established 3 territory franchise location. Franchisees operate a design-consultation business that brings soft and hard flooring samples, along with window treatment options, directly to customers’...

Greenville, SC

This franchise resale is an established residential flooring sales and installation business operating three territories across four counties in South Carolina's Upstate. Rather than a retail...

Greenville, SC

This is not a concept-stage or pre-launch opportunity. It is an established, operating mobile aircraft detailing and appearance-care business that has already completed difficult market-entry work and...

Greenville, SC

$9,074 Average Ticket and Over 100 5-Star Google Reviews with 100% Perfect Rating This is an established, open, and operating three-territory franchise resale in the home services space in Greenville,...

Greenville, SC

Full service exterior cleaning provider, ready for new management. Company has 20 years of building our customer base, with a large portion of our income being recurring revenue. We have a customer...

Greer, SC

Established Corrugated Manufacturing Business - 37 Years of Excellence Since 1989, this well-established corrugated packaging manufacturer has built a reputation for delivering innovative boxes and...

Greenville, SC

Pink Bee is an established women’s specialty boutique located in Greenville, South Carolina, offering a curated selection of premium apparel, accessories, handbags, shoes, and gifts. Known for its...

Greenville County, SC

Lean independent insurance agency in Greater Greenville with an approximately $1.5M P&C book generating ~$150K in annual revenue. The portfolio is heavily focused on personal lines, with 85% auto and...

Available in South Carolina

Work from home and build a scalable shipping business with UPS & DHL-low overhead, big income potential!

Greenville, SC

This business provides home support services including property upkeep, housekeeping, and home modification work for seniors and active families. A subscription model supports recurring revenue while...

Greer, SC

Nearly 30 years in business (established 1998) with a loyal, repeat customer base 4.9-star Google rating and outstanding local reputation Family-owned and operated since founding Turnkey operation —...

Greenville County, SC

Established South Carolina Bike Shop - Turnkey Operation in Growing Market This well-established bicycle retail, service, and rental business has been serving Greenville County since 2014, generating...

Greenville, SC

Excellent opportunity to acquire a growing 1-800-Striper franchise serving the highly desirable Greenville, Anderson, and Spartanburg County markets. This B2B pavement striping business offers a...

Greenville, SC

For 2 decades this company has operated from Greenville to Augusta and in Atlanta. Providing design services which leads to the sale of interior furnishings such as lighting, rugs, and custom...

Greenville County, SC

A great opportunity to purchase an established The UPS Store franchise in Greenville County South Carolina - without all of the initial startup costs and concerns. The 2025 revenues exceeded $405,000....

Greenville, SC

Our Shop have been busy, we've a lot of loyal customers return, most of our customers has a higher income, trust us that made our business daily went by fast. Our shop location one mile to Greenville...

Greenville County, SC

A great opportunity to purchase an established The UPS Store franchise in Greenville County South Carolina - without all of the initial startup costs and concerns. The 2025 revenues exceeded $405,000....

Simpsonville, SC

Established, Profitable Estate Sale Business Serving the Growing Upstate South Carolina Market This is an exceptional opportunity to acquire a well-established estate sale business serving the rapidly...

Greenville County, SC

This home-based B2B franchise established in February 2025 serves manufacturers and distributors in an exclusive Greenville, SC territory. Operating as a one-stop source for industrial packaging,...

Available Nationwide

Wonderly Lights presents a unique franchise opportunity tailored to your entrepreneurial preferences, allowing you to run a seasonal addition to your business portfolio or a stand-alone, year-round, full-service outdoor lighting business. Our seasonal holiday lighting services provide an especially attractive opportunity for those balancing their time with another seasonal venture.

Greenville, SC

Turnkey 3D/4D Ultrasound Boutique for Sale – Fully Equipped & Ready to Scale Rare opportunity to own a fully operational 3D/4D ultrasound boutique with an established brand, existing client base, and...

Greenville County, SC

Greenville first and ONLY 100% halal and kosher restaurant. Serving mouth watering dishes like 100% authentic lamb gyros , Lamb chops, chop cheese, wings and a whole wide range of menu items including...

Greenville County, SC

Deal Structure: Owner Operated Store - Selling Price $400k for Business. Inventory is Separate and can be brought down to agreed upon amount. SBA can cover large portion of the Price for Qualified...

Greenville County, SC

Bring All Offers! Seller Highly Motivated, looking to Relocate ASAP. Price of $150,000 includes the Inventory. Seller is willing to negotiate the price. Owner Operated Vape and Tobacco Business on one...

Greenville County, SC

Well-established Italian Restaurant located in Upstate South Carolina. This is a Hand-On Business for an Owner who likes to cook Pizza and Pasta! With a small intimate staff, the overhead is low and...

Available in South Carolina

An Opportunity to Buzz About: Meet the demand for custom window treatments with low start-up costs & high revenue potential—backed by HorsePower Brands

Greenville County, SC

Deal Structure: Price $1,318,000, Down Payment of $700,000 for qualified Buyers with $618,000 Seller Note. Seller is willing to stay on as Technician. Own this well-established HVAC company with a...

Greenville, SC

PRICED TO SELL; One of Greenville's most unique food venues with a huge customer base that continues to grow. Seller has other business investment opportunities that needs his full attention. The...

Greenville, SC

With over 1000 centers – and more opening each week – Mathnasium is rapidly growing in neighborhoods around the world. That’s because we are passionate about what we do. It’s also because our...

Greenville, SC

Geiss & Sons Jewelers was one of Greenville's best-known independent jewelry stores for more than three decades. Located at 765 Haywood Road, the family-owned business built its reputation on fine...