Health Care and Fitness Businesses For Sale in South Carolina

Senior PCA,Home Health & Hospice Care Franchise/$0 Fee Veteran Program

Pioneering Health and Wellness License Opportunity We are the true one stop shop for wellness. We offer more tools and modalities then anyone in or around the market - COMPRESSION - PEMF - INFRARED...

$35,000

Senior PCA,Home Health & Hospice Care Franchise/$0 Fee Veteran Program

Are you interested in a healthcare career? And if you are a veteran, transitioning military member, or spouse, we want to help you join our military-connected $0 Fee Veteran Program with no upfront...

$30,000

Stretch Your Success: Turnkey Stretch Zone Studio for Sale in Aiken

$30,000

Expansive Corner Lot | Single-Tenant

Auction by Ten-X™

Orangeburg, SC

Online auction: July 13-15, 2026

24,860 SF Freestanding For Sale...

Not Disclosed

Starting bid:

Not Disclosed

REAL ESTATE INCLUDED

Aiken, SC

Successful Stretch Zone franchise studio offering practitioner-assisted stretching services in the thriving Aiken, SC market. This turnkey operation generates $387,000 in annual revenue through a...

$70,000

Mobility City

Available Nationwide

Mobility City is the nation’s premier repair, rental, sanitizing and retail sales company servicing wheelchairs, mobility scooters, power chairs, lift out chairs, hospital beds and other mobility products.

$100,000

Acquire a Flourishing Senior Relocation and Property Clearing Business

Conway, SC

This sounds like a senior move management and estate liquidation business. It helps older adults and their families downsize, relocate, sell remaining household contents, and prepare the former home...

$199,900

Cash Flow: $154,912

Turnkey Group Fitness Studio – Recurring Revenue, Near-New

Fort Mill, SC

This group fitness franchise studio located in Fort Mill has a full team in place and a 2023 buildout that looks and operates like a new facility. The studio is part of a globally recognized...

$225,000

Cash Flow: $15,471

High-Growth Indoor Pickleball Club Opportunity

Charleston County, SC

This Southeast-based enterprise operates a premier, state-of-the-art, newly opened Pickleball facility specializing in the nation’s fastest-growing court sport. Revenue is projected to be over...

$1,500,000

Cash Flow: $147,784

Established, Open & Operating Home Healthcare Franchise Resale

Mount Pleasant, SC

We are an established, open and operating home healthcare franchise business for resale. We are a healthcare staffing service that helps families and businesses live and perform their best. We help...

$550,000

Premier (NEMT) Provider in South Carolina

Charleston County, SC

*** NOT SBA ELIGIBLE – IF PLANNING TO OR NEED TO USE AN SBA LOAN FOR ACQUISITION, PLEASE DO NOT INQUIRE *** Sale Price is 3x SDE + FFE Value (vehicle value) Highly Sought-After Industry: Excited to...

$825,000

Cash Flow: $170,900

William Bruce, ABI, SVA

William Bruce Business Sales & Acquisiti

Serving Richland County, SC

With offices in Fairhope, Alabama and Baton Rouge, Louisiana, William Bruce Business Sales & Acquisitions, LLC is a full service, national business brokerage and valuation firm serving privately held businesses with special attention given to pricing, strategic marketing, successful negotiation and prompt closings, all the while maintaining strict confidentiality. The firm is a "boutique" advisory service handling ONLY the sales, mergers and acquisitions of businesses with documented earnings. In reviewing any offerings by this firm, you can be assured that the numbers have been proven and are real. William Bruce currently serves as president of the American Business Brokers Association, an organization of over 7,400 professionals. Email: Will@WilliamBruce.org Website: www.WilliamBruce.org Fairhope, AL. Office (251) 990-5934 Baton Rouge, LA Office (225) 465-5799

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Turnkey 3D/4D Ultrasound Boutique for Sale

Greenville, SC

Turnkey 3D/4D Ultrasound Boutique for Sale – Fully Equipped & Ready to Scale Rare opportunity to own a fully operational 3D/4D ultrasound boutique with an established brand, existing client base, and...

$85,000

Comprehensive Home Care Services, Proven Operations & Demand

Greenville, SC

This care services company helps clients stay comfortable and independent at home through a range of non-medical in-home support. Backed by a strong track record and loyal client base, it offers a...

$249,900

Cash Flow: $236,100

Turnkey Stretch Studio Franchise - Transform Lives (And Your Career)

Simpsonville, SC

Established and growing, one-on-one assisted stretching facility located in a high- growth, high earning demographic region within the Greenville, SC metro area. Greenville, SC is consistently...

$125,000

UPDATED: Anytime Fitness franchise gym for sale - Strong model

Easley, SC

I have been a franchisee with Anytime Fitness for roughly 8 years. I own multiple businesses, and have been scaling down over the past 3 years to narrow my focus, allowing myself more time with my...

$199,000

Cash Flow: $30,000

10 Years Strong Thriving CycleBar Franchise for Sale

Greenville County, SC

This is an established, highly successful CycleBar location that has been in business for 10 years, profitable from day one, and now contains a 30,000-person email database and 300 loyal members....

$99,000

Cash Flow: $130,000

Get In Shape For Women

Available in South Carolina

Get In Shape For Women is an upscale, boutique fitness concept, where 1 trainer works with up to 8 women at a time, for 55 minutes, for as little as $20 per session, delivering the most compelling results in the shortest amount of time. We combine weight training, cardio, nutrition, and accountability for a complete solution.

$50,000

Ultrasound Studio & Boutique

Pickens County, SC

Own this Incredible Cycling Studio with Top of the Line Equipment, Growing Community of Members, and Unbeatable Location! Since 2023, this Business has been building a Community of Loyal Members who...

$195,000

Cash Flow: $14,765

Horry County, SC

Turnkey Ultrasound Studio + Brand Revenue Extension | Dual Revenue, Prime Location, Growth-Ready! Step into ownership with confidence—this fully operational ultrasound studio and semi passive revenue...

$315,000

Cash Flow: $101,988

Nurse Staffing Agency

Charleston, SC

Well Established Medical Staffing Agency Connecting medical staff with health care facilities across the nation since 2020...

$249,000

Body Sculpting- Licensed Med Spa business, Business professionals

Comprehensive Residential Care Provider with Proven Client Loyalty

Join the fastest growing mulit-billion dollar aesthetics industry with starting a body contouring med spa! You do not need to be a doctor or have a medical background. We teach you how to hire a...

Not Disclosed

North Charleston, SC

This dynamic home support business delivers both non-medical and medical in-home assistance, empowering clients to maintain their independence and comfort with tailored, compassionate care. Leadership...

$261,750

Cash Flow: $355,858

World renowned fitness branded gym with yearly competitions.

Horry County, SC

Fully equipped Crossfit gym, fully equipped with infrared sauna and cold plunge....

$225,000

Cash Flow: $75,000

Well established ophthalmology practice for sale

Columbia, SC

Well Established Ophthalmology Practice for Sale This thriving ophthalmology practice, established in 2006, represents an exceptional opportunity to acquire a well-positioned medical business in...

$425,000

Oral Surgery Practice Low Country, SC

Charleston County, SC

Oral Surgery Practice Low Country, SC Listing ID 1456858 $1,085,000 Description Fantastic opportunity to purchase a well established Low Country Oral Surgery office in South Carolina. Located in a...

$1,085,000

High-Demand Data-Driven Swing Studio for Serious Improvement

Charleston, SC

This data-driven swing studio supports golfers in making steady, measurable improvements through detailed TPI assessments, TrackMan technology, focused short-game practice areas, and fitness programs...

$575,000

Cash Flow: $145,909

Specialty Independent Footwear Store with Great Reputation

Horry County, SC

Specialty Footwear Store with Great Reputation and Motivated Seller!! This well-established specialty footwear retailer presents an exceptional opportunity in a thriving downtown district. Operating...

$225,000

Cash Flow: $100,000

Skyhawks Sports Academy

Available in South Carolina

Skyhawks low initial investment and low royalty fees allow our franchisees to see a return on their investment in a timely manner.

$60,000

Seasoned Cash Cow Fitness Club

South Carolina

The Club has 24 hour access. The club is located in a high-traffic retail strip center. It has an abundance of parking and easy ingress and egress. The location lends itself to membership consistency....

$1,600,000

Cash Flow: $410,000

Beautiful Hot Yoga Studio

Greenville County, SC

Are you looking to invest in a thriving health and wellness business? Look no further than this established Fitness Yoga Studio in South Carolina, United States. With a successful track record and a...

$115,000

Boutique Gym SBA Approved | Established Recurring Revenue

Charleston County, SC

Established boutique fitness studio specializing in personal training and small group sessions, located in an affluent area of Charleston. The business has built a strong brand over 10+ years,...

$72,500

Cash Flow: $52,644

Multi-Unit Franchise—Fitness Related

Horry County, SC

Turnkey opportunity to acquire 3 established fitness-related business locations serving the highly desirable Myrtle Beach market. As part of a respected national brand with nearly 400 locations and...

$700,000

Cash Flow: $235,000

Lexington Stretch Zone & rights to Florence

Sumter, SC

Columbia and Lexington stores are fully operational and staffed. Can sell both together or can break it up to only one store. Florence SC, I own the rights to the market, the store just needs to be...

$50,000

Senior Helpers

Available Nationwide

The premiere provider of in-home care where you can provide a lasting impact for aging adults and their families. Over 300 franchise owners! Open within 90 days!

$60,000

Established Multi-Location Fitness Brand | CHS County

Charleston County, SC

This is an exceptional opportunity to acquire a two-location fitness brand in Charleston County, located in highly desirable, high-traffic areas. Both locations are fully built out (approximately...

$400,000

Cash Flow: $89,000

Lake Murray, SC Chiropractic Practice for Sale

South Carolina

Enjoy strong disposable income with a low-overhead chiropractic practice designed for efficiency and ease of ownership. This clinic features elegant aesthetics that support patient retention, a highly...

Not Disclosed

Cash Flow: $431,000

Profitable Non-Medical Home Care Business in Myrtle Beach

Myrtle Beach, SC

Imagine owning a thriving home care business that's been serving Myrtle Beach families for 12 years. This isn't just any business opportunity - it's your chance to make a real difference in seniors'...

$280,000

Cash Flow: $100,000

Well-Established Chiropractic Practice

Charleston, SC

This is an opportunity to acquire a long-established chiropractic practice serving the Charleston market since 1989. The practice has built a loyal patient base over decades and is well known in the...

$247,000

Cash Flow: $95,000

Two Location Optometry Practice For Sale

Lexington County, SC

This reputable optometry practice has been serving its community for over 40 years with two well-established locations in growing areas. The practice enjoys strong patient demand, booking appointments...

$500,000

Cash Flow: $363,495

Michael Norman

The CBA Group

Serving Spartanburg County, SC

At The CBA Group we are Full-Time Business Brokers who work with our Clients until we complete our task for you. We are very sensitive to our Client's Confidentiality and we always do our part to protect all parties involved. We have a combined 81 years of Business Ownership and we understand what it means to Buy or Sell a Business. We always treat our Clients with the utmost respect and we are committed to working diligently assisting them in meeting their goals. We have helped Clients from Pennsylvania to Florida in achieving their goals and we continually strive to prove that competent Business Brokerage is needed and achievable. We offer assistance in obtaining funding for our clients, improving operational profits for our Clients, Consultation on operational matters, M&A transactions, assistance in Franchising, Buy and Sell transactions and Commercial Real Estate transactions.

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South Carolina Medical Transport Business

South Carolina

Providing non-emergency medical transportation services to enhance accessibility to healthcare. The company serves a diverse clientele, ensuring patients receive timely and safe transit to medical...

$1,100,000

Cash Flow: $353,944

Established Pediatric Therapy Clinic in Growing Charlotte Suburb

York County, SC

Available for purchase is a well-established, much-loved, community-based Pediatric Therapy Clinic offering physical, occupational and speech therapy to children from birth to age 18. This clinic...

$225,000

Cash Flow: $91,500

Pre-Revenue AI Powered Tech Business Focused on Mental Health Services

Charleston, SC

Proprietary AI powered therapist/client referral matching platform to establish and retain client-therapist relationships for therapeutic success available for sale. 6,500 vetted therapist members....

$1,800,000

Premium Boutique Fitness Studio – Profitable, Established & Poised for

Charleston County, SC

This is a rare chance to acquire a thriving boutique fitness studio located in a high foot traffic end-cap space within one of the most desirable and affluent communities on the coast. With over 8...

$160,000

Cash Flow: $108,999

Highly Profitable (HIIT) Class and Personal Training Gym FOR SALE!!!!!

Myrtle Beach, SC

Well established franchise (HIIT) Fitness Class and Personal Training Gym available for immediate sale in the Myrtle Beach area. Built In clientele, a full staff or trainers and central location make...

$110,000

Cash Flow: $45,404

A Better Solution In Home Care

Available in South Carolina

Where care and opportunity meet. Unlock wealth and purpose with our expert Home Care Model. We offer a Fully Passive Managed option.

$55,000

Oral Surgery Practice Low Country, SC

South Carolina

Oral Surgery Practice Low Country, SC Listing ID 1456858 $1,085,000 Description Fantastic opportunity to purchase a well established Low Country Oral Surgery office in South Carolina. Located in a...

$1,085,000

Turnkey fully set up Urgent Care Medical Clinic Fort Mill, SC

Asset Sale

Fort Mill, SC

This Business opportunity is a turnkey fully set up and established Urgent Care Medical Clinic since 2024. Located in York County, SC, the Clinic is currently closed due to an unforeseen family...

$150,000

Full Service Fitness Facility & Gym

Asset Sale

South Carolina

Full-service fitness facility and gym for sale. Includes all equipment and FF&E. The facility is 26,000 SF and includes a large weight/ aerobics area, racketball courts, and a full gymnasium. It is...

$1,800,000

Columbia MSA 7.25 Acre Commercial Dev. Site in Prime location!

Real Estate Only

Irmo, SC

New Offering on the Market. Approximately 7.25 acre site zoned general commercial with 625 feet of frontage on Broad River Road. Site has municipal water and sewer available with favorable topo for...

$895,000

Fitness Center, Pool and Event Venue

Real Estate Only

Beaufort County, SC

A rare investment opportunity conveniently located in the heart of SC lowcountry, just minutes from historic downtown Beaufort, SC. This offering includes a fully operational wellness club, saltwater...

$4,850,000

FYZICAL Therapy & Balance Centers

Available in South Carolina

FYZICAL is the largest Physical Therapy franchise in the U.S. Their unique Balance & Fall Prevention Program differentiates them. No medical experience required.

$100,000