Businesses For Sale in Buffalo, NY

Buffalo, NY

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$1M+ Net Profit Hair Restoration Clinic with No Medical Exp. Req.

Buffalo, NY

This is a niche and very high cash flowing established business opportunity in an industry that has been and continues to grow aggressively each year with very little competition. Through the use of...

$475,000

Cash Flow: $1,200,000

$475,000

Cash Flow: $1,200,000

Busy Retail Pharmacy

Buffalo, NY

PROFITABLE RETAIL PHARMACY - BUFFALO, NY Exceptional acquisition opportunity featuring a high-performing pharmacy generating $5,000,000 in annual revenue. Established in 2000, this busy retail...

$1,900,000

Lender-Driven Retail or Redevelopment

Auction by Ten-X™

Tonawanda, NY

Online auction: September 28-30, 2026

26,000 SF Supermarket For Sale...

Not Disclosed

Starting bid:

Not Disclosed

REAL ESTATE INCLUDED

Well Established Convenience Store With Pizzeria/Deli

REAL ESTATE INCLUDED

Buffalo, NY

Great Turn Key Opportunity To Own A Well Established Convenient Store with Pizzeria/Deli Business With Real Estate. Grocery/Restaurant/Deli Operation In Business Since 1939!! Over 35,000 Vehicles Per...

$650,000

REAL ESTATE INCLUDED

Weight loss and wellness center - Selling Below Startup Costs

Buffalo, NY

Great opportunity to purchase a Wellness franchise for less than the cost of opening a new location. Located in a well-known Buffalo shopping area with strong surrounding businesses, good visibility,...

$299,900

Turnkey Draft Beer Line Cleaning Business

Buffalo, NY

Thriving Draft Beer Line Cleaning Business The business services the metropolitan Buffalo NY area and has been in existence since 2017. It provides 2 and 4 week scheduled draft line maintenance for...

$85,000

Cash Flow: $41,000

8,800+/- SF Turnkey Restaurant & Hospitality Opportunity

Buffalo, NY

Own a Landmark Restaurant Property in the Heart of North Buffalo. Positioned in the heart of Buffalo's renowned Hertel Avenue dining and entertainment district, 1435 Hertel Avenue presents a rare...

$1,800,000

28-Year Category Leader | $13MM Revenue | $1.44MM SDE | In-House

Buffalo, NY

28-Year Category Leader | $13MM Revenue | $1.44MM SDE | In-House Transworld Business Advisors presents a 28-year-old, founder-owned online retailer generating approximately $13 million in annual net...

$5,795,000

Cash Flow: $1,442,293

20 year Established Dog Care Business. Easy, Profitable and Scalable.

REAL ESTATE INCLUDED

Buffalo, NY

Picture yourself owning a beloved neighborhood institution that's been caring for dogs for two decades. This isn't just any pet business - it's the place where families trust their furry companions,...

$499,900

Cash Flow: $50,000

REAL ESTATE INCLUDED

Electrical Repair And Maintenance Company In Buffalo

Buffalo, NY

This well branded electrical installation and repair business shows no signs of slowing down. The sale price includes (2) service vans plus an extensive equipment package. The local business serves a...

$209,990

Cash Flow: $175,000

Menchie’s

Franchise

Available in New York

Own a high-performing retail engine. Proven systems, consistent repeat traffic, and a brand built for long-term equity in a simplified category.

$120,000

Avg. Unit Revenue: $594,743

Priced to Sell! Turn-key Restaurant Opportunity - Buffalo, NY

Buffalo, NY

Highlights: • Fully equipped restaurant • 2,043 square feet • Busy plaza location • Ample parking and strong visibility • Equipment valued at approximately $40,000 included • Monthly lease of $4,256 •...

$50,000

Storage And Moving In One

Buffalo, NY

JUST LISTED!! (Summer 2026) Located in Rochester, NY, Monroe County TURNKEY OPERATION Well-run! Well-staffed (roster of ten or twelve active movers and staff)! Well-running equipment and vehicles...

$575,000

Cash Flow: $200,000

Property Damage & Restoration Company In Buffalo

Buffalo, NY

Operating on a multi-tier, multi-revenue structure, the business initiates with professional carpet and floor cleaning and extends to encompass property damage and restoration services, including...

$499,950

Cash Flow: $386,700

Thriving Appliance Ventilation Care Business

Buffalo, NY

This is a focused and efficient home services business providing professional dryer vent cleaning and maintenance for both residential and commercial clients within a growing segment of the property...

$290,000

Cash Flow: $131,819

Established Save-a-Lot Grocery Store!

Buffalo, NY

Established grocer in bustling urban neighborhood! Nearby competitors, like Guercio's, Rite Aid and Dollar General, have closed, leaving this store as the only local grocer that is larger than a...

$150,000

Cash Flow: $120,000

Bethany MacLean

Cynergy Consulting Services, Inc.

Serving Erie County, NY

Trust in our brokerage expertise to navigate the complexities of selling a medical practice. We have successfully brokered the sale and transition of over 2000 medical practices, making us the go-to choice for providers seeking top-notch service. Did you know there are strategic steps you can take to significantly increase the value of your practice before listing it for sale? Most providers are unaware of these opportunities. At Cynergy Consulting, we know the secrets to enhancing your practice’s worth, ensuring you get the most from your sale. Our comprehensive Intermediary Services (practice brokerage and sale), as part of a physician’s exit strategy, allow doctors in solo or group practice to convert the hard-won equity in their practices into liquidity, which can then be diversified for purposes of retirement or investment. Most physicians choose to stay with their practice under a negotiated employment contract for a number of years after sale. All physicians over age fifty-five (55) should have an exit strategy to ensure that they can capture the full value of their medical practice before they begin to “wind down”. Our staff has facilitated the sale of hundreds of medical practices over the last forty years in all fifty (50) states.

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Cybersecurity - Prevention and Incident Response; Turnkey with IP

Buffalo, NY

Highly successful full-service cybersecurity firm with an established national customer base. Unlimited growth potential Intellectual Property: Standard Operating Procedures for full-scope analysis of...

$3,000,000

Perfect Cafe Business for an Owner-Operator

Buffalo, NY

Step into a thriving community-centered café that delivers both financial returns and meaningful impact. This established coffee shop positions you to capitalize on the growing specialty coffee market...

$160,000

Cash Flow: $58,223

Unique Business

REAL ESTATE INCLUDED

Buffalo, NY

67 year old custom manufacturing and assembly business. Staffed with 9 qualified professionals. 7 Full time and 2 part time employees. Servicing: banks, schools, fire departments, police departments,...

$780,000

REAL ESTATE INCLUDED

23 FedEx Ground Routes - Buffalo, NY - Seller & Vehicle Financing

Buffalo, NY

The Asking Price for all routes, including 23 vehicles, is $150,000 in outright cash, plus $550,000 in estimated possible vehicle financing, plus $550,000 in seller financing (Total Purchase Price:...

$1,250,000

Cash Flow: $778,331

Truck and Trailer Repair Company

Buffalo, NY

Established truck and trailer repair company. Specializing in full service on heavy-duty, medium and light duty equipment. NYS inspection machine available. Commercial tractor and semi tractor. 7...

$795,000

Amazing Athletes

Franchise

Available in New York

Own a mobile youth sports franchise delivering programs inside preschools and childcare centers with recurring enrollment.

$50,000

Avg. Unit Revenue: $158,366

Coffee-Bakery Cafe for Sale

Buffalo, NY

New Price!!! Beautifully done with many upgrades! Does a very nice business with lots of parking. 3,000 Sq. Ft. building. Serving all sorts of coffees and pastries. Plenty of indoor seating and just a...

$130,000

Maytag Laundry: Mixed use - Laundromat, building and rentals

REAL ESTATE INCLUDED

Buffalo, NY

This established mixed-use commercial property represents a compelling investment opportunity in Buffalo's Bailey-Lovejoy district. The asset comprises a neighborhood laundromat operation with 25...

$699,900

REAL ESTATE INCLUDED

2467 Clinton St. - Self Serve Car Wash

Buffalo, NY

Attention Acquisition Entrepreneurs! Stake your flag in one of the most sought after Business Uses in today’s Marketplace. There is unlimited potential and plenty of opportunity to enhance, add Value...

$599,000

Well Established Wholesale and Retail Store For Sale

Buffalo, NY

This well established wholesale/retail clothing and footwear store offers quality clothes for work, schools medical, etc. Many years in business and makes money. 5,000 Sq. Ft. building. Many accounts....

$990,000

Turnkey Plowing & Landscaping company

Buffalo, NY

A well-established, fully operational plowing and landscaping business, in Buffalo, with a strong reputation and loyal customer base is now available for sale. Founded in 2018, this company has built...

$395,000

Cash Flow: $638,626

Restaurant For Sale

Buffalo, NY

Unique and very cool restaurant in the North Towns, Kenmore NY area. Rent is $2,500 a month and seats 32 to 58. Outdoor patio for summer dining. Weekly sales $4,000 to $6,000. Has beer and wine...

$150,000

General Contractor/Heavy Construction

Buffalo, NY

Open Shop Focus on water and water treatment Mostly municiple and government projects...

$5,500,000

Cash Flow: $1,300,000

Restaurant for sale in the Elmwood District of Buffalo NY

Buffalo, NY

One of Elmwoods Restaurant hot spots for sale in Buffalo NY. Great food with great service. Yearly sales of approximately $800,000. 60% sales are online ordering and 40% take out. Low rent of $2,050...

$340,000

Established and Profitable Cafe in Great Location

Buffalo, NY

Imagine yourself running this charming neighborhood café where the aroma of freshly brewed coffee greets you each morning. You'll love the warm, inviting atmosphere that keeps customers coming back...

$265,000

Cash Flow: $133,700

Party Rental Company For Sale

Buffalo, NY

Equipped for Weddings, Birthdays and many other events. Price of $49,500 includes; active bookings, equipment and nice truck....

$49,500

Toastique

Franchise

Available in New York

Join one of the fastest-growing, most simple-to-run healthy fast-casual restaurants!

$300,000

Avg. Unit Revenue: $614,256

Pizzeria for Sale (Well Established)

Buffalo, NY

Well established Pizzeria in a nice plaza location. Sales of $820,000+ yearly. 8 employees, nice menu and will train. Price of $390,000 includes business and equipment...

$390,000

Used car Dealership For Sale In Great Location

REAL ESTATE INCLUDED

Buffalo, NY

Used Car Dealership has been in business 40 years Annual sales of $6,000,000 10,000 Sq. Ft. building Turnkey and fully operational with inspection machine...

$2,400,000

REAL ESTATE INCLUDED

New York Turnkey Cannabis Processing & Distribution Business For Sale

Asset Sale

Buffalo, NY

New York Turnkey Cannabis Processing & Distribution Business For Sale w/ Established Retail Network! (Buffalo, New York) #2056 Position your business for immediate growth with this turnkey, licensed,...

$1,100,000

Party Supply Company

Asset Sale

Buffalo, NY

Own your own business that is fun to operate and makes people happy!. Established full service operation, From birthday parties to corporate events. Rentals include: tables, chairs, bounce houses and...

$180,000

Former Bar With Residence

Real Estate Only

Buffalo, NY

Stately Kaisertown Residence- Property was completely remodeled and updated while retaining the character of the past. 1st floor is the original bar with mirrors, lights, dart board, pool table,...

$419,999