San Bernardino, CA
Established in 1989 and operating from its current location since 2003, this long-standing multi-specialty medical practice is a highly reputable, high-volume operation serving a diverse and growing...
EBITDA: $874,000
Medical Practices For Sale in California
Multi-Provider Primary Care & Sleep Medicine Practice in Southern CA
Outpatient Physical Therapy Business for Sale.
Los Angeles, CA
Rare opportunity to acquire a well-established outpatient physical therapy clinic operating successfully since 2010 in Los Angeles, CA. This profitable, turnkey practice generates $501,000 in annual...
Cash Flow: $41,750
2
South California Behavioral Health Practice, Multiple Locations
San Bernardino County, CA
Established in 1999, this Southern California behavioral health practice generates approximately $4,000,000 in annual revenue with $550,000 in EBITDA. The practice operates as a multidisciplinary...
EBITDA: $550,000
San Francisco Facial Plastic Surgery Clinic for Sale
San Francisco, CA
San Francisco offers a premier market for facial plastic surgery, supported by a dense, affluent population and consistent demand for elective procedures. This established cosmetic surgery clinic has...
Cash Flow: $400,000
Multi-Provider ENT & Sleep Medicine Practice in Santa Maria, CA
Santa Maria, CA
This highly successful, long-established ENT and Sleep Medicine practice has been serving the community since 1990 and is recognized as the premier otolaryngology, sleep medicine, and audiology center...
Cash Flow: $946,000
Mobile Drug Testing Service - High-Demand Healthcare Business
Santa Clara County, CA
This thriving health screening enterprise provides comprehensive testing solutions to corporate clients and individual customers throughout the San Francisco Bay Area. The business specializes in...
Cash Flow: $115,000
Dental Office For Sale
Lawndale, CA
DENTAL OFFICE FOR SALE - PRIME LAWNDALE LOCATION Established dental practice operating since 2016 in a high-visibility corner shopping center in Lawndale, CA. This general practice dental office...
15
San Francisco Bay Area Neurology Practice for Sale
Contra Costa County, CA
The San Francisco Bay Area offers one of the most dynamic healthcare markets in the country, with a large patient population, strong insurance coverage, and consistent demand for specialty medical...
Cash Flow: $290,000
Sacramento Plastic Surgery Clinic for Sale
Sacramento, CA
Rare opportunity to acquire a thriving, 100% cosmetic facial plastic surgery and medspa practice in the heart of the growing Sacramento metro area. This well-established practice serves 3,300 active...
EBITDA: $492,361
Sacramento Plastic Surgery Clinic for Sale
Sacramento, CA
Rare opportunity to acquire a thriving, 100% cosmetic facial plastic surgery and medspa practice in the heart of the growing Sacramento metro area. This well-established practice serves 3,300 active...
Cash Flow: $571,648
ATC Healthcare Services
Franchise
Available in California
If you’ve got business savvy and a passion for helping others, ATC Healthcare Services offers a healthcare staffing agency to take your entrepreneurial spirit to new heights!
San Francisco Facial Plastic Surgery Clinic for Sale
San Francisco, CA
San Francisco offers a premier market for facial plastic surgery, supported by a dense, affluent population and consistent demand for elective procedures. This established cosmetic surgery clinic has...
EBITDA: $105,000
Advanced Psychological and Behavioral Medicine Center FOR SALE!
Downey, CA
This is a unique opportunity to acquire a fully established and thriving Advanced Psychological and Behavioral Medicine Center. Specializing in comprehensive mental health services, the center has a...
18
Fully operational turnkey Medical-Spa for sale!
Thousand Oaks, CA
High quality aesthetic medical spa and skin care clinic offering facials, laser hair removal, fat reduction, body sculpting, PDO threads, PRP (platelet-rich plasma), and face contouring. We provide...
Cash Flow: $190,000
14
Joint Commission Approved 6-Bed Detox Facility in Northridge
Asset Sale
Los Angeles, CA
Joint Commission Accredited, Advance Life Recovery is a licensed 6-bed residential detoxification and treatment facility in Northridge, CA, approved for clinically managed withdrawal management and...
57
DHCS & Joint Commission Licenses ONLY! EXCELLENT STANDING!
Asset Sale
Orange County, CA
Empower Retreat Center is no longer operating at the current location. This listing is for the sale/transfer opportunity of valuable treatment center licensing assets, including DHCS licensing and...
Dev Isemeyer
First Choice Business Brokers Los Angeles
Serving Los Angeles County, CA
As a Franchisee/Broker at First Choice Business Brokers, I help Main Street to Lower-Middle-Market businesses with proven business models and cash flow find strategic exits. I have been active in starting, scaling, and exiting businesses for over 3 decades having successfully facilitated deals across various sectors, including technology, transportation, manufacturing, retail, and franchise sales.
Contact me
Own a MedSpa Without a Medical License - Proven System, $50K-$100k+/mo
Start Up
Own a piece of the $20 billion medical aesthetics industry without a medical license, without franchise royalties, and without figuring it out alone. The MedSpa Launch Program by InjectableBoost.io is...
3
Concierge Practice in Affluent Coastal Community
Rolling Hills Estates, CA
This is a rare opportunity to acquire a long-established concierge primary care medical practice in a highly desirable coastal Southern California community. The practice, Macer Medical, has been...
Profitable Family & Sports Medicine Practice – Folsom, CA
Folsom, CA
A rare opportunity to acquire a well-established and highly profitable integrative family and sports medicine practice in Folsom, California—one of the most desirable and fastest-growing suburbs of...
6
Cash Flow: $266,000
Family Practice For Sale in California
Santa Barbara County, CA
REF#755 Located in desirable Santa Barbara County, this well-established family practice has been serving the community for over 40 years and has built a strong reputation with a loyal patient base...
Cash Flow: $194,283
Buy and/or Manage a Dream Medical Practice over 5000 patients in LA
Los Angeles, CA
This is the perfect opportunity for an entrepreneurial candidate to buy a business that has been a steady and consistent money maker for decades. The current owner is looking to retire due to provable...
Homewatch Caregivers
Franchise
Available in California
Recognized in the 2026 Entrepreneur Franchise 500, Homewatch CareGivers is a recession resilient in-home care franchise where owners average $2,599,498** in gross revenue while building meaningful, impact driven businesses.
Chiropractic Practice for Sale in California
Alameda County, CA
ref#727 Located in an attractive and highly desirable area of Alameda County, California, this well-established chiropractic practice presents an excellent opportunity for a doctor or investor seeking...
Cash Flow: $201,348
$450k SALE PENDING. Concierge Medicine & Vascular Clinic in La Jolla.
San Diego, CA
Well-established outpatient clinic for sale in a highly desirable coastal San Diego market. Fully contained and operational. -Unique 4-in-1 (four clinics in one facility) opportunity including a...
5
Established General Dental Practice of 20 years in Fremont
Fremont, CA
ESTABLISHED GENERAL DENTAL PRACTICE - FREMONT, CA Well-established general dental practice serving the Fremont community for over 20 years. This turnkey opportunity offers a proven business model with...
Ambulatory Surgical Center Accredited
Los Angeles, CA
Fully Accredited by Joint Commission -Ambulatories Outpatient Surgical Center for Sale – Prime LA Silverlake Location Asking Price: Negotiable. The owner would like to retire. The seller is also...
2
ENT Practice for Sale in California!
San Mateo County, CA
ref#790 Located in the heart of Silicon Valley and surrounded by an affluent community, this well-established ENT practice offers an exceptional opportunity for growth. With $1,072,889 in gross...
Cash Flow: $743,529
Established Bay Area Cosmetic Surgery Practice
Alameda County, CA
Transworld Business Advisors of Fremont DRE# 02194963 presents: Rare opportunity to acquire an established Bay Area cosmetic surgery and aesthetic medicine practice with approximately 20 years of...
Cash Flow: $204,480
Profitable Acupuncture & Functional Medicine Practice- Mill Valley, CA
Mill Valley, CA
An opportunity to acquire a long-established acupuncture, functional medicine, and integrative health practice serving Mill Valley and the greater Marin County community. Founded by Dr. Barbara...
5
Cash Flow: $160,329
Established Optometry Practice For Sale
Los Angeles County, CA
You could step into a Great Opportunity nestled in Southern California's San Fernando Valley. This practice is ideal for someone who wants to be their own boss, have work-life balance with schedule...
4
(Sale pending) — Rancho Mirage Med Spa
Rancho Mirage, CA
Desert Medical Rejuvenation is a profitable boutique medical spa located in Rancho Mirage, California—one of the most affluent communities in the Greater Palm Springs region. The practice generates...
6
Cash Flow: $216,163
2 Accredited Franchised Chiropractic Locations
San Diego County, CA
ESTABLISHED / TWO-LOCATION CHIROPRACTIC BUSINESS UNDER FRANCHISE BRAND PROFITABLE. STAFFED. TURNKEY OPERATIONS. Opportunity to acquire two established chiropractic clinics operating under a nationally...
Cash Flow: $150,000
WCH Service Bureau
Franchise
Available Nationwide
WCH Medical Billing Franchise: proven model, software, training, and step-by-step support to operate and scale.
Amazing Family Medical Practice with 43.5% EBITDA Margins
Orange County, CA
A well-established cardiovascular medical practice has operated for over 30 years in Southern California. It specializes in internal medicine, advanced diagnostic cardiology, and Enhanced External...
Cash Flow: $1,175,413
Long Established ADHC for Sale – Expansion Potential
San Bernardino County, CA
Adult Day Health Care program located in a prime Inland Empire location (San Bernardino County) with approximately 20 years of operating history (originally licensed in 2003). The center is currently...
In-Home Applied Behavior Analysis Therapy Provider
San Diego, CA
A leading provider of in-home early intervention and ABA services, the Company delivers individualized, evidence-based care to children from infancy through age eight, supporting critical...
Cash Flow: $723,928
Award Winning Northern Californian Chiropractic Care Center
California
This fully equipped Chiropractic Care Center is a California Sub Chapter S Corporation and has been in operation for 34 years and under current ownership for the past 18 years. They offer a wide...
2
Cash Flow: $310,000
Established Medical and Cosmetic Practice
Los Angeles, CA
This established practice in West Los Angeles/Brentwood combines an full-service Family Medicine practice with a cosmetic medical practice Both are under the supervision of the physician but the...
Cash Flow: $370,000
Send Me a Pro
Franchise
Available Nationwide
Send Me a Pro is the first Home Services Platform Franchise, enabling you to aggregate multiple home services under one franchise.
Profitable Podiatry Practice–Established 40 Years–Seller Retiring
Oceanside, CA
This established Podiatry Practice generates approximately $170,000 in annual seller discretionary earnings while currently operating on a part-time schedule, offering an excellent income opportunity...
Cash Flow: $170,000
Established and Profitable Endocrinology Practice for Sale
San Diego, CA
A Legacy of Care: Seeking a Qualified Successor for a Thriving, Office-Based Endocrinology Practice in San Diego Are you an entrepreneurial endocrinologist ready to take control of your career and...
Cash Flow: $600,000
Turnkey Chiropractic Business
Tehama County, CA
This well-established, highly respected chiropractic practice has been successfully serving the community for decades. Known for its exceptional patient care and consistently great reviews, this...
Cash Flow: $109,885
Palm Springs Podiatry – Seller Retiring April
Palm Springs, CA
Unique opportunity to acquire a 48-year established podiatry practice in Palm Springs, California. Dr. Dennis Lee Marta has built a respected, “low-tech, high-touch” practice rooted in decades of...
Cash Flow: $138,489
Top Ranking Weight Loss, Body Contouring and Aesthetics Med Spa
San Jose, CA
Established Weight Loss, Body Contouring and Aesthetics Med Spa Established in 1990 and owned since 2004, this highly regarded weight loss clinic and medical spa has become a trusted destination in...
5
Cash Flow: $365,000
Stan Cortland
CURB
Serving Contra Costa County, CA
Transforming Dreams into Reality
Contact me
Established Fast Growing Medical Spa For Sale
Temecula, CA
******Please be aware that this is a medical facility and would require the new owner to hold a medical license or have a medical director on staff that must own at-least 51% of the business*****...
6
EBITDA: $510,000
Medicare-Certified Home Health Agency – LA County | Clean | No ADRs
Van Nuys, CA
Turnkey Medicare-certified home health agency available in Los Angeles County. Established provider with active license and clean operating history. Key Highlights: • Medicare-certified (since 2021) •...
Clinical Laboratory approved by Medicare and CA Medical
Santa Ana, CA
Established Clinical Laboratory with Medicare and Medi-Cal Approvals - Santa Ana, CA This fully operational clinical laboratory presents an exceptional opportunity in Orange County's thriving...
Licensed Alcohol & Drug Residential Rehab Center w Real Estate!
REAL ESTATE INCLUDED
SBA LOAN ELIGIBLE
Corona, CA
LICENSED RESIDENTIAL REHABILITATION FACILITY WITH REAL ESTATE - RIVERSIDE COUNTY This exceptional real estate opportunity presents a fully licensed 6-bed residential alcohol and drug rehabilitation...
25+ Year Optometry Practice | Retirement Transition | in Ojai, CA
Ojai, CA
This is a rare opportunity to acquire a long-standing, 25+ year, profitable optometry practice with no direct competition within a 15-mile radius. The 2 other practices in the area have had...
Cash Flow: $157,000
SYNERGY HomeCare
Franchise
Available in California
The average annual gross sales for a SYNERGY HomeCare multi-territory franchise operation in business for over 1 year is $2,116,737. $2,116,737 is the average gross sales of 141 mult-territory businesses (478 territories) that have been in operation for all of 2025. 54 Businesses (38%) met or exceeded the average annual Gross Sales. There is no assurance, however, that you will do as well. See item 19 of our Franchise Disclosure Dcoument.
Plastic Surgery & Aesthetic Practice – Profitable, Cash-Pay, excellent
Beverly Hills, CA
A board-certified plastic surgery practice in 1998 and established a solo practice in 2000 at the same location. The practice is organized as an “S” corporation. Approximately 80% of his surgeries are...
Cash Flow: $575,000
Profitable Physical Therapy & Acupuncture Clinic
Los Angeles County, CA
Rare opportunity to acquire a well-established, profitable physical therapy and acupuncture clinic in the heart of the South Bay, Los Angeles. Sunshine Rehabilitation Center has been owned and...
Cash Flow: $161,190
Medical Spa Turnkey- High volume area!
Sacramento, CA
This beautifully maintained 2,300 sq. ft. medical spa features eight fully equipped procedure rooms, two restrooms, and a dedicated laundry room. Located in a high-traffic shopping center next to...
4
Cash Flow: $200,000
LA County ADHC – 160 Capacity | 100+ ADA
Los Angeles County, CA
Fully licensed Adult Day Health Care (ADHC) center located in Los Angeles County (South Bay Area) with a licensed capacity of 160 participants. The program operates at a stable average daily...
Step into Ownership: Established Pediatric Therapy Clinic
Orange County, CA
Established Pediatric Therapy Clinic - Prime Orange County Location This thriving pediatric therapy clinic represents an exceptional opportunity for healthcare professionals seeking ownership of a...
6
USA Ninja Challenge
Franchise
Available Nationwide
Build a thriving kids’ fitness business with USA Ninja Challenge. Membership-based recurring revenue, proven support, and a mission that empowers every child.
Buy or Sell a Medical Practice in California
Medical practices listed on BizBuySell include solo practitioner offices, multi-provider clinics, and specialty healthcare businesses across primary care and fields such as dermatology, pediatrics, optometry, chiropractic care, physical therapy, pain management, oncology, endocrinology, and surgery. Business models range from insurance-based practices to cash-pay clinics and hybrid models. Many listings feature established patient panels, credentialed staff, EMR systems, insurance billing infrastructure, and long-standing referral networks. Revenue is typically generated through patient visits, diagnostic services, procedures, and ancillary offerings. Some practices also include real estate, medical equipment, or turnkey operations—providing licensed professionals and healthcare investors with opportunities for growth, stability, and long-term value in the healthcare services market.
| Market Overview | Listings for Sale (Median) |
|---|---|
| Number of Businesses Analyzed | 65 |
| Asking Price | $580,000 |
| Reported Revenue | $991,550 |
| Reported Seller's Discretionary Earnings | $303,492 |
Financials based on businesses that listed an asking price, annual revenue, and seller's discretionary earnings.
Asking Price
| Lower Quartile | Median | Upper Quartile |
|---|---|---|
| $355,000 | $580,000 | $1,200,000 |
Market Financial Highlights
The financial data presented here is an aggregation of reported revenue and earnings of Medical Practices for sale in California.
| Bound | Revenue | Seller’s Discretionary Earnings |
|---|---|---|
| Lower Quartile | $511,081 | $171,054 |
| Median | $991,550 | $303,492 |
| Upper Quartile | $1,834,750 | $580,650 |
Valuation Multiples
The valuation multiples listed below are derived from asking price, revenue, and seller's discretionary earnings of Medical Practices listed for sale in California.
| Bound | Revenue Multiple | Earnings Multiple |
|---|---|---|
| Lower Quartile | 0.63 | 1.60 |
| Median | 0.87 | 2.24 |
| Upper Quartile | 1.09 | 3.17 |
FAQ's
How much does it cost to buy a Medical Practice in California?
The median asking price for an established Medical Practice in California is $580,000, though prices range from under $355,000 to well over $1,200,000.
How much do Medical Practices owners in California earn?
The median reported revenue of Medical Practices in California is $991,550 and owners earn a median of $303,492, which includes the owners salary and any other financial benefits they receive.
How do I value a Medical Practice?
Valuing a business is a complex process, but buyers and sellers often turn to the local market to understand how businesses are priced. Based on our most recent analysis of Medical Practices in California, revenue multiples range from 0.63 to 1.09, with a median of 0.87. Earning multiples range from 1.60 to 3.17, with the median at 2.24. This means the typical Medical Practice in California may ask for around 0.87 times its annual revenue, and 2.24 times its annual owner earnings.
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