South Carolina

Businesses For Sale in South Carolina

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3 Profitable Axe Throwing Stores, High Growth Areas

South Carolina

Fun for all ages. All skill levels can compete. Looking to sell all 3 stores as a package....

$249,000

$249,000

Cash Flow: $163,000

Downtown GVL Hot Spot

Greenville, SC

This is a rare opportunity to acquire a well-established, highly profitable downtown restaurant in the heart of Greenville, one of the fastest-growing and most desirable small cities in the Southeast....

$499,000

$499,000

Cash Flow: $233,000

Established & Reliable Commercial Cleaning Services for Sale

York County, SC

Imagine walking into a business that's already proven itself in the cleaning market. This established commercial cleaning service has built something special - real relationships with clients who...

$325,000

$325,000

Cash Flow: $98,720

Coastal Ale House - For Sale

Conway, SC

SIZE: Restaurant building 3,200 sq ft. with Approximately 172+ seats indoors/outdoors; Includes fully equipped kitchen (all FF&E), 4 Fryers, 2 Flat top grills, setup for high volume. 14 Beer Taps at...

$1,600,000

$1,600,000

Greenville NY Style Pizzeria in a Fantastic Location

Greenville, SC

Turn-key NY-style pizzeria in a prime Greenville location. Bring your concept to one of the fastest-growing and most desirable markets in the Southeast. This fully equipped New York–style pizzeria...

$149,000

$149,000

Confidential Restaurant – James & Johns Island Area

James Island, SC

Confidential Restaurant Opportunity – James and Johns Island Area Asking Price: $399,000 Opportunity to acquire a fully built-out restaurant located within one of the Charleston region’s...

$399,000

$399,000

CPA Firm with a Strong Reputation and Exceptional Team

South Carolina

-One CPA partner willing to stay on to run daily operations -Nearly 100% paperless with efficient, scalable systems -Annual fee increases already in place providing predictable revenue growth -Young,...

$1,150,000

$1,150,000

Profitable Contract Manufacturer for Sale

South Carolina

The Hatteras Group is pleased to represent PROJECT RAM for sale. For more than two decades this company has provided contract manufacturing to a wide variety of industries. Services include in house...

Not Disclosed

Not Disclosed

EBITDA: $1,600,000

Greenville Restaurant with Parking

Greenville, SC

Discover a unique opportunity to own a charming freestanding restaurant in vibrant downtown Greenville, SC. This attractive property boasts rare private parking for 10 vehicles—an invaluable asset in...

$299,000

$299,000

Cash Flow: $65,000

Long-Established Precision Machining Business with Real Estate

REAL ESTATE INCLUDED

South Carolina

This established manufacturing operation offers a solid foundation in the precision components sector, with decades of reliable performance serving industrial clients. It provides a ready-to-operate...

$3,300,000

$3,300,000

REAL ESTATE INCLUDED

NW Columbia, SC Chiropractic Practice for Sale

South Carolina

Enjoy strong disposable income with a low-overhead chiropractic practice designed for efficiency and ease of ownership. This clinic features elegant aesthetics that support patient retention, a highly...

Not Disclosed

Not Disclosed

Cash Flow: $431,000

Established Residential Home Inspection Business | 17 Years Strong

Newberry County, SC

This well-established residential home inspection company has been serving its market since 2008, building a strong reputation and consistent referral base. With 350–400 inspections performed annually...

$250,000

$250,000

Cash Flow: $85,000

North Charleston Restaurant with Real Property in Booming area!

REAL ESTATE INCLUDED

No Chas, SC

Walk into your own thriving restaurant in one of North Charleston's most exciting growth areas. This isn't just another business opportunity - it's your chance to step into a beloved neighborhood...

$1,325,000

$1,325,000

REAL ESTATE INCLUDED

High Cash Flow Plumbing Company – Coastal South Carolina

Charleston County, SC

Established plumbing services company operating in a high-growth Coastal South Carolina market with a strong reputation, repeat customer base, and consistent service demand. The business provides...

$1,479,000

$1,479,000

Cash Flow: $416,000

21 FedEx P&D Routes - Upstate South Carolina

South Carolina

Own a large, profitable operation with a full-time manager! › 21 Trucks › 1 Manager › Value of fleet included in asking price. › Full-time manager on staff to handle the daily operational tasks of the...

$2,500,000

$2,500,000

Cash Flow: $632,003

Heather Valeri, Broker of Distinction

Meridian Business Advisors

Serving Charleston County, SC

Ranked top 10 business brokerage firms in the USA and ranked #1 best business advisory firm in South Carolina. Meridian Business Advisors is a leader in industry. Whether you represent an acquisition-minded corporation, or are personally interested in owning your own company, our company offers the professional services that successfully bring buyers and sellers together. From business brokerage to mergers and acquisitions; we are the business experts. We strive for complete confidentiality and work with our clients through all phases before and after the sale to ensure a smooth transition. We are also an independent business brokerage company and a trailblazer for the industry. We strive to raise the bar on best practices, technology and service. We are powered by the EXP Realty global network. Plus, part of the top 10 real estate team in the USA- Legacy Group International with over $100m in real estate sales for 2025.

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Own This SC Restaurant Real Estate on Over 7 Acres!

REAL ESTATE INCLUDED

Greenville, SC

This Restaurant Real Estate for Sale near Greenville, SC offers a rare opportunity to own both the business and the property it occupies. Sitting on approximately 7.41 acres and offering around 4,600...

$1,299,000

$1,299,000

REAL ESTATE INCLUDED

Profitable High-Volume Freight & Logistics Business

REAL ESTATE INCLUDED

Greenville County, SC

~$500,000 in Earnings through 6-Months! (2026) This Greer, South Carolina-based freight and logistics operation has built a high-volume, multi-service transportation platform with deep roots in the...

$5,450,000

$5,450,000

Cash Flow: $622,000

REAL ESTATE INCLUDED

Restaurant For Sale

Myrtle Beach, SC

CONFIDENTIAL RESTAURANT FOR SALE Oceanfront | Myrtle Beach, South Carolina Outdoor Oceanfront Patio ASKING PRICE: $299,000 ESTIMATED MONTHLY OCCUPANCY COST • Estimated rent all in $6,800 per month...

$299,000

$299,000

Priced for Immediate Sale — Established HVAC Franchise

Simpsonville, SC

This is an opportunity to acquire an established residential HVAC franchise in the desirable South Carolina market, including Beaufort County, Hilton Head, Bluffton, etc. And the coast of Georgia from...

$309,000

$309,000

Mens formal clothing retail and rental business

Horry County, SC

This retail and rental boutique exclusively for men has been servicing locals and tourists for several decades. It boasts one of the largest inventories of formal wear in the area with fast turn...

$125,000

$125,000

Cash Flow: $98,000

2 High-Performing Cafés with Turnkey Franchise Platform!

Mount Pleasant, SC

Confidential Multi-Unit Café Brand + Franchise System for Sale! Prime Locations | $1.7M+ in Sales | Scalable Concept! An exceptional opportunity to acquire a well-established, multi-unit café concept...

$690,000

$690,000

Restaurant for Sale near Greenville, SC! Real Estate an Option

Greenville, SC

If you're looking for a Restaurant for Sale that's ready for your concept, this approximate 4,800 square foot location offers everything you need to hit the ground running. Whether you want to keep...

$99,000

$99,000

High-Traffic B2B Directory — Turnkey, Passive Income Opportunity

Berkeley County, SC

This home-based, high-traffic B2B directory is the largest of its kind and offers a turnkey opportunity to generate passive income through multiple revenue streams. The platform attracts more than...

$149,000

$149,000

Cash Flow: $7,800

Blythewood Veterinary Clinic – Established & Profitable!

Blythewood, SC

Overview: Established and highly reputable veterinary clinic located in Blythewood, SC, serving a growing community with comprehensive small animal care. This turnkey practice offers a rare...

$1,500,000

$1,500,000

Prime Opportunity to own an Allstate agency with multi-state footprint

South Carolina

Imagine stepping into your own successful Allstate agency that's already hitting all the right notes. This isn't just another insurance business - it's your chance to own a proven winner in Upstate...

$1,490,000

$1,490,000

198 Okatie Village Dr - For Sale

Okatie, SC

Restaurant for Sale- No. 1 China Prime Location in Okatie, SC 198 Okatie Village Dr, Suite 101, Okatie, SC 29909 Asking Price: $72,000 Rent: $3,900 Key Highlights: Location: Situated close to Hilton...

$72,000

$72,000

Prime Mount Pleasant Location

Mount Pleasant, SC

Buyout Price: $125,000 Monthly Rent: $4,500 Square Footage: 1,200 SqFt Property Highlights: No hood system required, offering flexibility for non-vented cooking operations. Includes walk-in cooler and...

$125,000

$125,000

Yoshi Poke & Kitchen

Charleston, SC

SIZE: This restaurant is approximately 1,200 square feet. The restaurant has a fully-equipped and open kitchen concept. There is a 16-foot hood system within this space. The restaurant has outdoor...

$125,000

$125,000

Restaurant for Sale in Downtown Charleston, SC

Charleston, SC

CONFIDENTIAL RESTAURANT LISTING – DOWNTOWN CHARLESTON, SC LOCATION: Upper King District – Downtown Charleston, SC DESCRIPTION: An exclusive opportunity to acquire a fully built-out, turnkey restaurant...

$399,000

$399,000

Up-to 30% Seller-Financing | 20-yr. Flexible Lifestyle Ad Business

South Carolina

Proven Model | Lifestyle Flexibility | Community Focus Seize a turnkey opportunity to own a longstanding direct mail advertising business in a growing South Carolina metro area, with over two decades...

$209,000

$209,000

Cash Flow: $80,000

Profitable Confectionery Retailer with E-Comm & B2B Growth

Charleston County, SC

This established confectionery business operates a brick-and-mortar retail store with in-house production and a growing e-commerce platform, specializing in premium, homemade sweets. It offers a...

$299,000

$299,000

Cash Flow: $100,000

Retail Liquor Store

Myrtle Beach, SC

This well-established retail liquor store represents a proven business opportunity in Myrtle Beach's competitive beverage retail market. The enterprise has been family-owned and operated,...

$149,900

$149,900

Specialty Window Coverings Sales/Installation #1997

South Carolina

In home service contractor specializing in the sales and installation of plantation shutters, shades, and blinds. Launched in spring 2020 this business has demonstrated a remarkable growth trajectory,...

$800,000

$800,000

Cash Flow: $256,608

Restaurant for Sale In Forest Acres! TurnKey Opportunity

Columbia, SC

Buy this second generation Restaurant for Sale in Forest Acres and take over a fully outfitted space at a fraction of the cost of a new buildout. Priced at just $69,995, this motivated seller...

$69,995

$69,995

Successful, established Day Spa with affluent Clientele

Greenville County, SC

Step into your own successful day spa where loyal, affluent clients already know and trust the brand you'll be taking over. This well-established destination spa has been carefully built over several...

$925,000

$925,000

Cash Flow: $320,000

Profitable Remodeling Business for Sale!

Myrtle Beach, SC

This is a well-established, profitable residential and light-commercial remodeling company with a multi-year operating history and a strong reputation for quality, reliability, and repeat business....

$750,000

$750,000

EBITDA: $188,077

Bargain Franchise Hamburger Restaurant

Georgetown, SC

This nostalgic themed hamburger restaurant is a locals favorite. Sales are consistently $700K +/ year, with a good $150K cash flow. Rent is a very reasonable $3474/ month. The franchise is family...

$210,000

$210,000

Cash Flow: $150,000

4500sf Downtown Charleston Restaurant with Sub $30psf base rent!

Charleston, SC

This exceptional 4,500 square foot restaurant space offers an attractive purchase opportunity in downtown Charleston's highly desirable Upper King Street corridor. The property is strategically...

$900,000

$900,000

Painting & Coatings Contractor w/ 5yr Transition

Horry County, SC

NOTE: ONE OF THE PARTNERS WILL STAY ON AS AN ON-SITE OPERATOR FOR UP TO 5-YEARS! Please also note that this business is NOT eligible for SBA financing. A father and son partnership has successfully...

$1,400,000

$1,400,000

Cash Flow: $397,294

Flooring Biz. Growing Market Area. Positive Cash Flow.

Horry County, SC

FOR SALE: is a profitable flooring replacement franchise. In biz since 2018. B2B2C: Its focus is residential and contractors. 50+ Google Reviews; 4.9 stars. Solid Revenues and enjoying Profits. An...

$210,000

$210,000

Cash Flow: $84,000

Joan Loch

Resource Business Brokerage

Serving Dorchester County, SC

Resource Business Brokerage was formed by Joan to fill a gap in the regional area of Wilmington to provide personalized service, education and consults to the small to medium business community. Buying or Selling can be a daunting undertaking that we know first hand about and in turn built our services around navigating the process for all parties involved. For business buyers we can help with lease negotiations, lending option and area information if relocation is in the picture. For business sellers we can help with property that is being sold along with the business, creating comps and market reports along with the business valuation needed to price the sale. We are professional and have "resources" and knowledge to get any project to the closing table.

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Turnkey Café & Retail Opportunity in Charleston's Highest-Traffic

Charleston County, SC

desirable and high-traffic locations. Positioned in the heart of a thriving commercial district, this business benefits from exceptional visibility, strong foot traffic, and an attractive long-term...

$249,999

$249,999

Cash Flow: $145,000

Handyman Franchise – Coastal South Carolina

South Carolina

HS Listing ID-68967 This is an opportunity to acquire a well-established Handyman franchise serving Horry County and Georgetown County, South Carolina (Myrtle Beach market). The business operates...

$698,500

$698,500

Cash Flow: $295,000

Profitable Established Charter and Taxi Transportation Business

Charleston, SC

THE CHARLESTON TRANSPORTATION LEGACY: A 30-YEAR SUCCESS STORY AWAITS ITS NEXT CHAPTER Nearly three decades ago, a visionary entrepreneur recognized Charleston's untapped potential in passenger...

$3,600,000

$3,600,000

Cash Flow: $250,000

Profitable Restaurant for Sale Strong Earnings! SBA Pre qualified!

Lancaster, SC

SBA PRE QUALIFIED! This Restaurant for Sale in Lancaster, SC offers a profitable opportunity for a new owner to step into an open and operating business with immediate cash flow. 2025 sales are...

$299,000

$299,000

Cash Flow: $143,361

Established Italian Fresh Pasta Market with Strong Catering Deman

Horry County, SC

One of a kind Italian market that offers fresh pasta, heat and eat prepared foods, ravioli, deli sandwiches, imported italian delicacies and a full line of catering. Perfect business for a working...

$389,000

$389,000

Cash Flow: $150,000

Ready To Go Restaurant for Sale in Growing Spartanburg Market!

Spartanburg, SC

This Restaurant for Sale in Spartanburg, SC offers a prime opportunity for a motivated owner operator or investor to step into a fully equipped, second generation restaurant space. Whether you're...

$69,000

$69,000

Profitable Non-Medical Home Care Business in Myrtle Beach

Myrtle Beach, SC

Imagine owning a thriving home care business that's been serving Myrtle Beach families for 12 years. This isn't just any business opportunity - it's your chance to make a real difference in seniors'...

$280,000

$280,000

Cash Flow: $100,000

Well-Established Chiropractic Practice

Charleston, SC

This is an opportunity to acquire a long-established chiropractic practice serving the Charleston market since 1989. The practice has built a loyal patient base over decades and is well known in the...

$247,000

$247,000

Cash Flow: $95,000

Allstate Agency in North Augusta, SC

Aiken County, SC

This meticulously grown Pro-level Allstate agency has $3.44M in premium and 1718 active policies. Retention is strong at 85.62 and with a 43 year client base in the North Augusta area, this agency is...

$630,000

$630,000

Established Hospitality Supply Wholesaler Serving the Southeastern U.S

South Carolina

This well-established wholesale supplier serves hospitality organizations across the Southeastern United States. The company provides a comprehensive range of linens, towels, housewares, small...

$1,250,000

$1,250,000

Cash Flow: $285,287

Buy a Small Business in South Carolina

When looking at South Carolina business for sale, you are best to consider the ideal location of the state. It is located in the southern states where weather is mild in the winter and sunny in the summer. It is known for its amazing beaches and rich historically significant sites. The tourism industry has maintained a stronghold, and there are plenty of opportunities to take advantage of the tourists who pack the state all year round.

South Carolina is seeing great growth in the number of working age people in the population. This is great news for this southern state and for business owners looking to move here. If you are considering South Carolina businesses for sale, then consider that this state is offering up a huge pool of workers to help you get your business off the ground. It also has an amazing shoreline and a nice tourism industry, which provides plenty of opportunities for business.

The biggest industry in the state by far is tourism. Not only is South Carolina offering prime beaches and recreation in the Myrtle Beach and Hilton Head areas, but the state also is rich in historical assets that make for wonderful vacation destinations, especially in areas such as Charleston. The low gas prices in the state don't hurt this industry either and can make buying a gas station a great option. Another area seeing strong growth is automotive manufacturing with the introduction of new plants and increased production. The economy is also expected to get a boost from construction projects in Charleston Harbor that will allow ships from the Panama Canal to enter the port.